A study of Xiao-xu-ming-tang. II Indications for Xiao-xu-ming-tang.

PI3K/Akt Pathway Contributes to Neurovascular Unit Protection of Xiao-Xu-Ming Decoction against Focal Cerebral Ischemia and Reperfusion Injury in Rats

In the present study, we used a focal cerebral ischemia and reperfusion rat model to investigate the protective effects of Xiao-Xu-Ming decoction (XXMD) on neurovascular unit and to examine the role of PI3K (phosphatidylinositol 3-kinase)/Akt pathway in this protection. The cerebral ischemia was induced by 90 min of middle cerebral artery occlusion. Cerebral infarct area was measured by tetrazo...

Erratum to “Xiao-Xu-Ming Decoction Protects against Blood-Brain Barrier Disruption and Neurological Injury Induced by Cerebral Ischemia and Reperfusion in Rats”

Xiao-Xu-Ming decoction (XXMD) is an effective prescription in the treatment of ischemic stroke, but the mechanisms involved are not well known. In the present study, 120 male Sprague-Dawley rats were randomly divided into 5 groups: sham control (sham), ischemia and reperfusion (IR), and IR plus 15, 30, and 60 g/kg/day XXMD. The stroke model was induced by 90 min of middle cerebral artery occlus...

Understanding the polypharmacological anticancer effects of Xiao Chai Hu Tang via a computational pharmacological model

Xiao Chai Hu Tang (XCHT), a traditional herbal formula, is widely administered as a cancer treatment. However, the underlying molecular mechanisms of its anticancer effects are not fully understood. In the present study, a computational pharmacological model that combined chemical space mapping, molecular docking and network analysis was employed to predict which chemical compounds in XCHT are ...

Size-dependent lattice structure of palladium studied by x-ray absorption spectroscopy

Chih-Ming Lin,1,* Tsu-Lien Hung,2 Yen-Heng Huang,3 Kung-Te Wu,4 Mau-Tsu Tang,5 Chih-Hao Lee,3 C. T. Chen,6 and Y. Y. Chen6 1Department of Applied Science, National Hsinchu University of Education, Hsinchu 30014, Taiwan, Republic of China 2Department of Physics, National Tsing-Hua University, Hsinchu 30013, Taiwan, Republic of China 3Department of Engineering and System Science, National Tsing-H...

Herbal Monograph for Xiao Chai Hu Tang , Part Two Pharmacological Effects